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So to answer your question directly, there are some people who probably don't have that thrifty gene, but just the fact of how their lifestyle is they're not physically active, they're eating a lot of highly processed food and so forth they're gaining weight, but that can change quickly depending upon change in their behavior and in their environment

A semaglutide user with low drive sits in a different place than a retatrutide user with elevated resting heart rate, chills, and brain fog

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Fast spiking interneuron control of seizure propagation in a cortical slice model of focal epilepsy