Reference [1]Wang, J
Excess LDL exposure increases the cholesterol uptake and growth of triple negative as well as ER-negative breast cancer cells [60, 101] and HDL can increase the growth and migration of ER-positive cells [65, 70]
Thus, this modest increase in LDL-C may be misleading regarding ASCVD risk, as patients with obesity may have a higher concentration of atherogenic small, dense LDL particles, and therefore high levels of apoB for a given blood LDL-C [10, 13]
However, this benefit was not observed in all-cause death, hospitalization for HF, CV death, MI, stroke, and death or hospitalization for HF ( The benefits of GLP-1 RAs in HF may be explained in terms of their weight reduction properties
& Karami-Mohajeri, S
Proline accumulation has been reported during various stress conditions, including drought 18 and heat 19