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A major observational study published in mid-2025 found that diabetic patients taking GLP-1 drugs faced a two- to threefold higher risk of developing nAMD compared to non-users

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These three actives have indeed shown that they are capable of improving microcirculation, via different mechanisms: caffeine accelerates blood circulation, vitamin K strengthens vascular walls, thus promoting lymphatic drainage and microcirculation, and immortelle essential oil inhibits the synthesis of nitric oxide, a compound contributing to fluid stagnation

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