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Feeling cold during retatrutide treatment is most plausibly linked to rapid or substantial weight loss and reduced caloric intake , rather than a direct pharmacological effect on thermoregulation

Some may be linked to the indirect effects of rapid weight loss, such as muscle loss and joint instability

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BPC-157 decreased TNF-, IL-6, and IL-1 levels in tissue samples

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As you and your body get accustomed to the medications and some possible side effects, well increase the dose appropriately up to what your body can tolerate without surpassing the maximum allowed limit of 2.4 mg/week for adults