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Fernando Ovalle Jr., a double board-certified plastic surgeon and obesity medicine specialist, explains that some nutrients and supplements can modestly influence appetite, blood sugar, or satiety pathways, but they act much more subtly than GLP-1 medications
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In the pre-specified 104-week extension, participants on 12 mg reached an average of -30.3% (-85.0 lbs / -38.5 kg) , with no weight-loss plateau observed
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61.9%, respectively) 34 and a post-hoc analysis of this trial showed a 6069% mean 10-years relative risk reduction of T2D development 75
Testing should include: Erythrocyte sedimentation rate, C-reactive protein, and antinuclear antibodies: though these are nonspecific markers of inflammation, they may support an immune-mediated etiology if positive Extractable nuclear antigen panel: Sjgren syndrome A and B autoantibodies are the most important components in this setting 5,11 The Schirmer test or salivary gland biopsy should be considered for seronegative patients with sicca or a suspected immune-mediated etiology, as the sensitivity of antibody testing ranges from only 10% to 55%
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