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1 Introduction Obesity is a multifactorial chronic disease characterized by excessive fat accumulation in adipose tissue, which can lead to insulin resistance, hypertension, and dyslipidemia ( via distributed neural pathways ( There are evidences shows GLP-1 analogues directly signal to adipose tissue

In addition, no significant differences in postprandial GLP-1 levels were observed between saline-treated and d-Lys3treated female Tmprss2 / and WT mice (Figure 2M)

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So, these short-chain fatty acids can be considered hormones