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Collectively, the composition, metabolic activity, and functionality of the gut microbiota significantly affect the metabolism of GLs

Med Microbiol lmmunol

This effect is part of the entero-insular axis of glucose homeostasis and is estimated to be responsible for at least 50% of insulin secretion [2, 3]

Approaches to the evaluation of lip hyperpigmentation

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This release is rapid, and is known to peak at around 10 min from the initial glucose challenge, whilst the second phase of insulin release, which is sustained, consists in the release of granules from the larger Reserve pool (RP), containing ~9599% of insulin granules, and lasts until glucose stimulation ends (3060 min under normal physiologic conditions) (35)