The FASEB Journal , 36
Its level decreases with age (especially from the age of 45-50) and as the body's defence needs increase (immunity, liver detoxification, antioxidant defences...)
(2) D Gwyer, N M Wragg, and S L Wilson (2019)
A study published in the Journal of Pineal Research documented the decline in pineal melatonin production in relation to Alzheimer disease progression
Conjugations with glutathione
In addition, Sekhar's work revealed that supplementing GlyNAC to older people and HIV patients reversed other abnormalities including inflammation, endothelial dysfunction, insulin resistance, and improved muscle strength, exercise capacity, cognitive decline, gene damage, and body composition