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Beyond WL, GCG agonism may be particularly beneficial for individuals with metabolic-dysfunction associated steatotic liver disease (MASLD) and MASH

An important consideration is that tirzepatide significantly delays gastric emptying, which can affect the absorption of oral medications

An appetite suppressant and stimulant, caffeine promotes weight loss by increasing metabolism and breaking down fats in the body, says Richardson

Levocarnitine, also known simply as L-carnitine, is a naturally occurring amino acid derivative that helps turn the fats we eat into energy

Keywords , MASH , GLP-1 receptor agonists , hepatic steatosis , metabolic dysfunction , tirzepatide , semaglutide , survodutide 0 2 INTRODUCTION Metabolic dysfunction-associated steatotic liver disease (MASLD), previously termed nonalcoholic fatty liver disease (NAFLD), has emerged as the predominant hepatic pathology worldwide, impacting roughly twenty-five percent of the adult population [1,2]

2.1 Genetic factors PCOS patients often have a family history and show a certain degree of familial clustering, suggesting a strong genetic component