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Thiamine (Vitamin B1) Essential for energy generation, brain and nerve function, and cardiac muscle activity

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Side effects and safety Reported side effects are generally mild injection-site reactions, flushing, headache, and water retention from elevated GH

Conclusion: The HAE-PLG patients who developed thrombotic events on AT were all elderly (over 65) and had cardiovascular history and risk factors

Most patients begin experiencing noticeable appetite suppression within one to four weeks of starting tirzepatide, though some individuals report subtle changes within the first week