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3 Materials and methods 3.1 Preparation of pentoxifylline-loaded chitosan nanoparticles (PTX-CSNPs) PTX-CSNPs were prepared using the ionic gelation method, exploiting the electrostatic interaction between positively charged chitosan and negatively charged sodium tripolyphosphate (TPP)

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Diet is the primary source of carnitine in humans, with only a small fraction being endogenously synthesized

Tolerance has not been observed in clinical use