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While some peptides naturally produce slightly turbid solutions, a dramatic increase in cloudiness compared to fresh material indicates degradation

doi: 10.1371/journal.ppat.1012188 95 WangYBJinCZ

Moreover, they are resistant to DPP-4 activity and have a longer half-life than native GLP-1

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Hence, complex formation between TBC1D9B and TMEM55B is mediated by multiple sites but does not involve the TBC domain that harbors its GAP activity