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Long-term treatment with low doses of GW-9508-another GPR40 agonist-decreased circulating glucose and insulin levels significantly, which resulted in improvements in glucose intolerance in high fat diet-induced diabetic mice [58]
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Pharmakokinetik von L-Carnitin
Dose optimization represents the first-line approachescalating to 1 mg weekly, and subsequently to 2 mg weekly for diabetes management or 2.4 mg weekly for weight management, often produces substantially better outcomes than remaining at 0.5 mg
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