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2a), and the percentage of fibroblasts in G0/G1 phase and the percentage of apoptotic fibroblasts did not significantly differ both in keloid fibroblasts and in normal skin fibroblasts ( p = 0.4, Supplementary Fig
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Our findings identified that the optimal duration for reducing FBG, HbA1c and HOMA-IR is 50 weeks, although this change was not significant for insulin levels
The oral bioavailability of PF-06882961 in animals was low to moderate and increased in a dose-dependent manner, which was adequate for studying preclinical in vivo efficacy and safety of PF-06882961 delivered via the oral route in standard formulations
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