GLP-1 receptor agonists, like semaglutide and tirzepatide, have helped many people manage weight and metabolic health more effectively, but if you're feeling tired, sluggish, or mentally foggy after starting treatment, you may not be alone
Verify the solution is clear (TB-500 may appear very faintly tinted)
Acknowledgements This work was supported by the Medical Research Council [grant numbers MR/J01186X/1, G0901321, MR/M006301/1], (the third grant is a UK New Investigator Research Grant supporting MJB)
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Management of fatigue in patients taking GLP-1 receptor agonists begins with thorough assessment to identify contributing factors and exclude serious underlying conditions
Then, 3.5 l of the sample was applied onto 45 s glow-discharged quantifoil grids and vitrified in liquid ethane using a Vitrobot Mark IV (ThermoFisher Scientific) at 100% humidity, 7 s blotting time and 10 s waiting time