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Campolo et al., 2017

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They're shifting in such a way that you become a bit testosterone dominant, even if you're low testosterone, but there's more of an assertiveness that comes out, and women can either take that by the reins and use it as a power, or sometimes the hormones are so out of whack and the metabolism is so out of whack that they just feel crazy and bitchy and completely out of line

For long-acting agents such as semaglutide, clinicians generally recommend stopping therapy at least two months before attempting pregnancy due to the extended half-life

Eur J Pharmacol 1005:178055 Sadeghian BE, Hayati RN, Anvari M, Ramezani TF (2023) Prenatal kisspeptin antagonist prevents PCOS

That said, there are exceptions, workarounds, and alternative paths worth knowing about