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This 28day guideline comes from the USP Compounding Standards, which sets standards for sterile compounding and states that an opened multidose vial with antimicrobial preservative should be discarded within 28 days unless the manufacturer specifies otherwise
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He had a chronic headache history but denied any recent exacerbations
Most formulas ignore that
Gastrointestinal symptoms are typically worst during early treatment and dose escalation, often improving within four to eight weeks at a stable dose
