It lowers the intraluminal concentration of poison in the GIT, creating a concentric gradient between the blood and bowel fluid, which increases the flow of poison from the blood to the GIT, a process known as gut dialysis
These approaches address the underlying metabolic dysfunction driving fat accumulation in the liver
Traveling internationally can create even larger disruptions
Anita Petruzzelli, M.D
Collectively, IGF2R-directed LYTACs exemplify a versatile and potent nanomaterial strategy for achieving targeted protein degradation, with applications spanning nucleic acid nanostructures, small molecule conjugates, liposomal delivery, and engineered proteins to overcome cancer resistance mechanisms
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