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butyricum improved intestinal barrier integrity by increasing the levels of TREK1, CLDN1, CNDN3, and OCLN tight junction proteins and reducing the levels of IL-6, TNF-, and IFN- in the colon, resulting in reduced ASD-associated behaviors [365]
& Gebel, H
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It is known that single residue changes in S proteins can alter protein structure, and from this, it is proposed that even mutations distant from the S1 protein may lead to modifications in the native disulfide-thiol balance [51]
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