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17 Interestingly, GLP-1 levels are elevated in critically ill patients in different chronic inflammatory diseases including CD, UC, metabolic syndrome, coronary artery disease, and heart failure, and have been found to be increased in animal models of inflammatory conditions in response to bacterial stimuli, suggesting a correlation between inflammation and GLP-1 secretion

Emerging mechanisms of neutrophil recruitment across endothelium

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These are open research questions, and the combination data come largely from preclinical and short-term studies that have not been validated in large human trials