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Anal Bioanal Chem 415 , 61456153 (2023)

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6 Challenges and future directions Clinical trials that employ the lifestyle changes and microbiota-based approaches discussed above are usually carried out in small cohorts

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In response to oxidative stress, the expressions of MT2A and HO-1 are heightened due to ROS

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One article proposed that excessive serotonin levels could explain classic symptoms of ME/CFS (433), as it would promote the release of excess CRH, and therefore cause chronic reactivation of the HPA axis (434)

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