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BMJ 345 , e5414 (2012)
Seek medical advice if you are taking B12 supplements and experience: Persistent skin changes, particularly acne-like eruptions or rosacea worsening Unexplained headaches or dizziness that coincide with supplement use Gastrointestinal symptoms including nausea or abdominal discomfort Any allergic reactions such as rash or itching Call 999 or go to A&E immediately if you experience: Difficulty breathing Swelling of the face, lips, tongue or throat Severe rash or itching Other symptoms of severe allergic reaction after taking B12 These symptoms warrant review of your supplementation regimen
Keep the vial upright to minimize stopper contact with liquid
At 10mg/ml (1ml water added): Draw 100 units
Here is a simple side-by-side of how long each method usually takes for common changes
