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Fatigue (low energy): This may be due to low blood sugar or reduced calorie intake, as Ozempic suppresses your appetite

The strongest signal available, he pointed out, is how much weight a patient loses early on: a drop of at least 5 pounds in the first three months "outperforms any known genetic marker." Who loses the most weight on Ozempic, and who loses the least Beyond DNA, a handful of ordinary clinical traits do a surprising amount of predictive work

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, triple board-certified in internal medicine, lifestyle medicine, and obesity medicine physician and internist at Beth Israel Lahey Health