Folate must be checked alongside B12, and folate deficiency should never be treated in isolation when B12 is low, because doing so can mask the anaemia while neurological damage progresses
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This is particularly relevant for oral administration, which is subject to intrinsic factor saturation and receptor limitations in the ileum ( Moreover, our results highlight the essential role of vitamin B12 in homocysteine metabolism, as supplementation was associated with a significant reduction in serum homocysteine levelsan important biomarker associated with cardiovascular and neurodegenerative diseases
For example, after a total gastrectomy, we recommend that patients get B12 supplementation often in the form of B12 injections for the rest of their lives
5 h skip large meals and intense exercise
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