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In summary, FOXO4-DRI exerts its anti-aging effects by inhibiting the binding of FOXO4 to P53, promoting P53 phosphorylation, and facilitating the translocation of p-P53 from the nucleus to the cytoplasm for its functional role
Pelaia, G
Peptides are typically large, hydrophilic, and often charged, so they cross membranes poorly by passive diffusion
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Ferroptosis is significantly different from the previously known apoptosis or autophagy in cell morphology, in which cell membrane rupture does not occur during ferroptosis
Randomized, double-blind, placebo-controlled study of brodalumab, a human antiIL-17 receptor monoclonal antibody, in moderate to severe asthma
