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The physiological plausibility

4.12 Iodine Iodine concentration is primarily regulated by the thyroid through the synthesis of T4 and T3 hormones, which are stored in follicular colloid (the body's main iodine reserve) and whose release is stimulated by TSH via a negative feedback mechanism

Sodium gluconate is a humectant, pH regulator, and chelating agent

Mechanism of action, pharmacokinetics, clinical efficacy and adverse effects

It nudges your pituitary in short bursts that resemble your body's own pattern

Replacement of Tyr110 in recombinant Y110A decreased both k cat app and 1/ values for the disulfide substrate and GSH in the GSSCys and HEDS assay (Supplementary Figs 18 and 19)