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[6] Gunawan M, Nuriza N, Kaiin EM, Sjahfirdi L

Diabetic wound models showed a 9-fold increase in collagen synthesis, better epithelialization, and activation of fibroblasts and mast cells

Increases in cGMP result in the inhibition of plasma membrane localized L-type Ca 2+ channels resulting in decreasing overall intracellular Ca 2+ which normally serves to activate myosin light chain kinase leading to vasoconstriction

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Side effects such as weight gain, dry mouth, and dizziness may be experienced

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