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Acknowledgements We thank the staff of the Animal Magnetic Resonance Research Center of the First Affiliated Hospital of Jinan University for performing the animal MRI scans

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External resources Phase 2 trial: Once-weekly cagrilintide for weight management (PubMed) REDEFINE 1: Coadministered cagrilintide and semaglutide in adults with overweight or obesity (NEJM) Development of cagrilintide, a long-acting amylin analogue (Journal of Medicinal Chemistry) For researchers serious about building evidence-based peptide protocols, SeekPeptides offers the most comprehensive resource available

Study Identification and Selection Approach The initial search yielded a large body of literature across peptide agents and clinical domains