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Growth hormone is the main example

10.4103/0250-474X.57282 219 MukhopadhyayS.HoidalJ

When the annulus tears or weakens, the nucleus can bulge or herniate, potentially compressing spinal nerves

5 Therapeutic strategies targeting shared metabolic pathways in sarcopenia and atherosclerosis The recognition of shared pathways necessitates a shift from single-disease management to integrated strategies targeting IR, chronic inflammation, lipid dysregulation, and hormonal shifts to disrupt the bidirectional vicious cycle (136) (As shown in Table 2 )

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