Serious adverse effects to monitor include pancreatitis, gallbladder complications, hypoglycaemia, and fluid retention
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References : Office of Dietary Supplements, NIH
The effect of selenium on thyroid status in a population with marginal selenium and iodine status
Coffee, even black coffee, reduces absorption and should be consumed at least 30 minutes after taking levothyroxine
The philosophy was that the larger gauge would stand a better chance of getting into the fat