PubChem CID 9831659 compound identity, modified sequence, formula, molecular weight, and identifier record
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The shRNA constructs against NRF2 were designed targeting guggcugcucagaauugcaga (sh NRF2 -1), guaagaagccagauguuaaga (sh NRF2 -2), and gcuccuacugugaugugaaau (sh NRF2 -3) (#230086 and 230087, Addgene)
Each removal from the refrigerator exposes the vial to temperature change and potential contamination
If iron is decreased and the TIBC is normal, the percentage saturation of transferrin will be low
This does not invalidate the data, but it means the evidence base is narrower than the publication volume implies