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The poly dopamine shell responds to a high ROS environment to release rutin, directly scavenging excess ROS within mitoROS, repairing disrupted ETC function, and stabilizing MMP, blocking abnormal opening of the mPTP and ferroptosis cascades, ultimately alleviating damage to renal tubular epithelial cells, significantly reducing serum LDH leakage, improving glomerular filtration function and histopathological damage, and achieving protective effects on IRI kidney function [57]

Aberrant transferrin and ferritin upregulation elicits iron accumulation and oxidative inflammaging causing ferroptosis and undermines estradiol biosynthesis in aging rat ovaries by upregulating NF-b-Activated inducible nitric oxide synthase: first demonstration of an intricate mechanism

The small airways of the lungs require glutathione to function properly

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Bias in meta-analysis detected by a simple, graphical test

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