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Medication eligibility, dosing, and duration are determined after clinical evaluation
Human clinical evidence was prioritized for synthesis, with preclinical evidence used to contextualize biologic plausibility
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Expected population level mortality impacts by age under the central scenario
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It is essential to devise strategies that could address the treatment landscape for kidney protection in T1D by assessing the risk-benefit calculus and expanding the nephrologists toolkit for minimizing kidney risk in T1D
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