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Efficacy of GLP-1rA, liraglutide, in plaque psoriasis treatment with type 2 diabetes: a systematic review and meta-analysis of prospective cohort and before-after studies
Int J Sport Nutr Exerc Metab
The activation of the classical cAMP pathway is achieved by releasing irritating G protein subunit Gs through the exchange of guanine nucleotide and the activation/dissociation of heterogeneous trimer G protein, and in pancreatic cells, GLP-1 binds to the specific guanine nucleotide-binding protein-coupled receptor GLP-1R, leading to adenylyl cyclase activation and elevated cAMP levels (Mayo et al., 2003
Reidelberger, R
Ferri 2014a)
In this review, we systematically searched major scientific databases (e.g., PubMed) for studies published within key timeframes relevant to each topic
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