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The region also benefits from a well-established supply chain for peptide raw materials, protected amino acids, intermediates, and specialized reagents, providing manufacturers with cost and operational advantages compared with many other regions

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715,716 In this section, we have summarized the findings of in vivo studies investigating the applications of probiotics (Table 1) and prebiotics (Table 2) in neurodegenerative disease models, with a specific focus on their effects on the intestinal barrier, BBB, and glial cells