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Non-DAC CJC-1295 mimics natural GH secretion and may reduce side effects like water retention or insulin resistance (Crane, N., Frontiers in Endocrinology )

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A 22% reduction in the risk of worsening kidney function, measured by a drop in estimated glomerular filtration rate (how much blood the kidneys filter clean every minute) of at least 50%

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Types of outcome measures Primary outcomes Primary outcomes included PD motor impairment as measured by the Movement Disorder Society-Unified Parkinson's Disease Rating Scale (MDS-UPDRS) subscale Part III in the on-medication state in endpoints and midpoints of included studies and in the off-medication state in endpoints and midpoints of included studies [19]

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Arch Biochem Biophys 595:6163 Kannan R, Chakrabarti R, Tang D, Kim KJ, Kaplowitz N (2000) GSH transport in human cerebrovascular endothelial cells and human astrocytes: evidence for luminal localization of Na+-dependent GSH transport in HCEC

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