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Importantly, GLP-1RAs do not exert direct immunosuppressive effects but instead modulate inflammatory pathways indirectly through metabolic and cellular mechanisms, supporting a favourable safety profile when used alongside bDMARDs

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Most people on an aggressive protocol find they want far less of it anyway, since the reward response to food and drink tends to soften across the board

(PubMed) Bodnar LM, Simhan HN, Powers RW, Frank MP, Cooperstein E, Roberts JM

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