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The likely causes include escalating FDA enforcement against research peptide vendors, ITC actions blocking peptide imports, quality concerns revealed by Finnrick testing (E-rated retatrutide across 37 samples), and the broader collapse of the grey-market business model

Crucially, the discrepancy between cancer incidence and risk shows that while the discovered correlations might not immediately result in a significant clinical burden of disease, they should not be discounted in the absence of additional long-term safety information

Blood 134 , 18 (2019)