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The MDD patient group comprising the discovery and validation sets consisted of 76 drug-treated (DT) or non-drug treated (NDT) patients

Top-line data will be presented at the CTAD conference on 3 December 2025, with full results to follow at AD/PD in March 2026

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The ammonia level of the patient decreased to 367 mol/l (625 g/dl) within 2 h and he exhibited spontaneous movement and neurological improvement within 1 h of starting CKRT 41

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