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Synthesis and study of L-dopa-glutathione codrugs as new anti-Parkinson agents with free radical scavenging properties

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[PMID: 1540213] PubMed record related to this compound for laboratory literature review

Higher mitochondrial metabolism in the neurons result in generation of Complex I dependent hydrogen peroxide and neuronal membranes, rich in polyunsaturated fatty acids, are particularly vulnerable to oxidative stress due to their possession of unsaturated double bonds

The presence of TFA can affect the peptide's net weight, appearance, and solubility

Due to limited cell numbers available, the samples from the in vitro and ex vivo studies did not always overlap