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Phentermine's known adverse effects include increased heart rate (tachycardia), elevated blood pressure, palpitations, insomnia, dry mouth, constipation, restlessness, and dizziness
And with weight gain comes the return of insulin resistance. If you discontinue the medication, lifestyle interventions can partially preserve insulin sensitivity improvements after you stop taking the meds, says Silvana Obici, MD, the chief of the division of endocrinology at Stony Brook Medicine and the medical director of the Stony Brook University Hospital Diabetes Center in New York
Retatrutide is expected to yield even better outcomes due to its broader impact on glucagon levels
When combined with GLP1 medications, patients often experience more effective targeting of stubborn belly fat, improved energy levels, and better overall body composition changes compared to either treatment used individually
Respir Physiol Neurobiol
Wegovy: A higher-dose injectable medication specifically approved for chronic weight management
