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If you have had difficulty tolerating semaglutide side effects or tirzepatide adverse events , cagrilintide alone may offer a smoother experience

You continue the medication that got you to your weight loss goal. Most side effects of GLP-1s are mild and temporary

Zhang Y, Sun B, Feng D, et al

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A 2025 Reuters piece described individuals mixing their own weight-loss drugs ordered from overseas suppliers ( [7] )

GLP-1s can create a catabolic (breakdown) state due to significant caloric restriction, leading to muscle loss