If thigh injection reduces nausea enough to keep you compliant with your protocol, the slightly slower absorption becomes irrelevant compared to the benefit of actually staying on treatment
However, there are limitations specific to this study in addition to its retrospective nature and relatively small proportion of patients treated with GLP-1 RAs
Yang S, Zhao X, Zhang Y, Tang Q, Li Y, Du Y, et al
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The rules that govern that decision are distributed across Section 801 of the Federal Food, Drug, and Cosmetic Act (21 U.S.C