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Oxidative stress exacerbates BBB disruption through activation of the inducible enzymes NADPH oxidase 4 (NOX4) and NOX5

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Meanwhile, Mn 2+ catalyzed H 2 O 2 to produce toxic OH through Fenton-like reactions under the assistance of HCO 3 2- and high temperatures, which was engineered by an MS-BSA-triggered photothermal effect, potentiating a GSH depletion-prompted robust anticancer effect

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Hydration will prevent further clogging

While these added ingredients can support overall skin health, results can vary depending on individual factors and consistent use