In mouse models of type 2 diabetes induced by a highfat diet and streptozotocin, 4 weeks of 5amino1mq injection reduced fasting blood glucose by 25%30%, increased insulin secretion by over 20%, and significantly decreased cell apoptosis
Inositol supports insulin regulation and fat metabolism, while choline aids in liver function and fat transport
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However, the independent effects of vitamin B12 on IR could not be interpreted from the mentioned trials due to combination therapy
This is the most common route for B12 in a clinic, usually into the deltoid muscle of the upper arm