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These findings provide further evidence of oxidative stress in the context of DS (Ishihara et al

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2002;282(2):E474-E482

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10.1016/j.cell.2012.03.042 Cell 46 Do VanB.GouelF.JonneauxA.TimmermanK.GelP.PtraultM.et al (2016)

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Enhanced TP53 Reactivation Disrupts MYC Transcriptional Program and Overcomes Venetoclax Resistance in Acute Myeloid Leukemias

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The 2010 analysis added a maintenance and re-treatment phase confirming durability and reversibility of effects

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10.1002/mnfr.201500537 61

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