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Understanding Our Tests: Hydrogen-Methane Breath Testing to Diagnose Small Intestinal Bacterial Overgrowth
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However, long-term human safety trials are lacking, so usage should be approached with caution
10.1038/s41571-021-00529-6 8
Despite these advances, critical challenges remain: distinguishing adaptive compensation from maladaptive remodeling, validating tissue-to-plasma concordance, establishing longitudinal human cohorts with serial metabolomics, and developing harmonized multi-omics pipelines
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