Participants will be randomized to receive either tirzepatide or a placebo by mail and will take it for a year
included at least two HbA1C measurements spanning at least one year
PLoS One 9 , e86219 (2014)
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Preclinical studies in rodents with long-acting GIP, GLP-1, and GLP-2 analogues, alongside related clinical trials, suggest these molecules are safe, and furthermore, may improve overall bone health