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doi: 10.1016/S2213-8587(14)70142-1 32 Corkery-HaywardMMetherellLA
Clinical trials show that appetite suppression can begin within the first few days of treatment, though the most significant weight loss results typically emerge after 4 to 12 weeks of consistent dosing
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An exploratory analysis of completed randomized trials reported that tesamorelin was associated with reduced intramuscular fat and increased muscle area in adults with HIV. Intramuscular adipose tissue can be relevant to muscle quality and metabolic function, but imaging-based changes do not necessarily indicate increased physical strength, improved athletic performance, or enhanced exercise recovery
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