Han DH, Kim WK, Lee C, Park S, Lee K, Jang SJ, et al
RA is known to increase levels of multiple cysteine/serine proteases, which lead to heightened extracellular proteolysis, in turn generating low-molecular-weight circulating peptides
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Subacute combined degeneration one century later
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Israel Chaikoff, an observation now known as the Wolff-Chaikoff effect (25, 26)